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Open Access Article
1 - Effect of MIIT training on visfatin and insulin resistance index in obese girls
Anahita Nafisi Bentolhoda Nasrabadi Mohammadreza MohseniBackground: Visfatin is a new adipocyte which is highly expressed in visceral adipose tissue and has similar effects with insulin in the body. The purpose of this study was to investigate the effect of moderate intensity interval training on visfatin and insulin resi MoreBackground: Visfatin is a new adipocyte which is highly expressed in visceral adipose tissue and has similar effects with insulin in the body. The purpose of this study was to investigate the effect of moderate intensity interval training on visfatin and insulin resistance index in obese girls. Material and Methods: In this semi-experimental study, 18 obese girls aged 12 -14 years were selected voluntarily and divided into two groups: training and control randomly. The training program included 8 weeks, 3 sessions a week, each week for 30 minutes running at 70% of the target heart rate in the first week to the fourth week and 75% in the fifth to the eight weeks. Blood samples were taken 24 hours before and 48 hours after the training program and the research variables were measured using specific methods. Analysis of covariance ANCOVA was used. The significance level was considered as p <0.05. Results:.The results of the current paper showed that the visfatin , Insulin resistance index, insulin and maximal oxygen consumption (vo2max) were increased in experimental group, which was significant only for the values of vo2max (P = 0.001). Body weight, body fat percentage, body mass index or BMI and glucose variables decreased in the experimental group. Conclusion: Today obesity is become a worldwide health issue and in this research paper we could show that longer training sessions with adequate intensity and volume have beneficial effects and they are suggested to make optimal changes in visfatin levels and reduce insulin resistance in obese girl. Manuscript profile -
Open Access Article
2 - The effect of eight weeks of High Intensity Interval Training (HIIT) on the expression of lipasin in diabetic rats
Sepideh Salehi Nikoo khosraviBackground: Diabetes is a metabolic disorder recognized as one of the most common diseases in the world. The disease has also increased dramatically in Iran.Today, there are many ways to treat diabetes, one of which is the increase in the level of pancreatic beta cells. MoreBackground: Diabetes is a metabolic disorder recognized as one of the most common diseases in the world. The disease has also increased dramatically in Iran.Today, there are many ways to treat diabetes, one of which is the increase in the level of pancreatic beta cells. The increase in these cells is done in several ways Several studies have demonstrated that the lipasin or betatrophin gene, a liver-expressed peptide hormone, increases the proliferation of beta cells, and that overexpression of this gene can increase the number of beta cells. Materials and Methods: The study was conducted on 16 Wistar rats with a mean weight of 160 ± 10. They were induced by diabetes (seven months of diabetes mellitus was caused in rats). They then were divided into two groups of 6: Control (C) and High-Intensity Interval Training (HIIT). Eight weeks of exercise training was conducted on rats.The qRT-PCR technique was used to investigate changes in lipasin expression. An Independent t-test was used for data analysis, and Pearson correlation was used to determine the correlation between lipasin expression and insulin resistance index (P <0.05). Results: The results showed that expression of lipasin gene in the liver of rats in the training group was significantly higher than the control group rats after 8 weeks of training; Insulin resistance index of plasma, plasma insulin and plasma glucose decreased considerably after eight weeks of HIIT. Between lipasin expression and insulin resistance index in rats with type 2 diabetes in the training group, a consider correlation has been observed. Conclusion: This study showed that an 8-week HIIT training period, with increased lipasin expression, could increase beta cells and also recover type 2 diabetes, which had been destroyed by these cells, and as a result of this increase in Insulin secretion and there is a way to prevent the disease. Manuscript profile -
Open Access Article
3 - The effect of L-arginine supplementation along with 6 weeks of Aquatic training on changes in blood pressure and fasting blood sugar in older peoples with Hypertension
Yaser Kazemzadeh Pegah Hooshangi Yasamin SoltaniBackground and purpose: The factors that control blood pressure, the most important of which are inactivity and improper nutrition. The present study was conducted with the aim of investigating the effect of arginine supplementation on blood pressure and glucose metabol MoreBackground and purpose: The factors that control blood pressure, the most important of which are inactivity and improper nutrition. The present study was conducted with the aim of investigating the effect of arginine supplementation on blood pressure and glucose metabolism in elderly people with mild Hypertension. Materials and methods: 43 elderly men and women in the age range of 55 to 70 years with mild hypertension were selected as participants and were randomly divided into 4 groups, including the aquatic training group (AT), L-arginine supplementation (ARG), aquatic training + L-arginine supplementation (AT+ARG) and control (CON). AT group did sports training in water for 6 weeks. ARG group received 100 mg of L-arginine per body weight and AT+ ARG group received L-arginine supplement during 6 weeks of water sports training. The control group also received only placebo. The values measured in the present study included aerobic power, systolic blood pressure, diastolic blood pressure and fasting blood glucose. The findings were compared using one-way analysis of variance and Tukey's post hoc test at a significance level of ≥0.05. Results: The findings of the present study showed that the diastolic blood pressure of the subjects did not differ significantly (P=0.239), but the difference between the systolic blood pressure of the group was significant (P=0.031). Also, the change of fasting blood glucose of the samples in the 4 groups shows a significant difference (P=0.011). L-arginine consumption group and sports training + L-arginine consumption group showed a significant difference with the control group (P=0.0001 and P=0.001, respectively). Conclusion: The results of the present study showed that consuming L-arginine for 6 weeks in the elderly with hypertension can lead to improvement of their systolic blood pressure and fasting blood sugar, but adding training cannot double its effect. slow All sports training have proven effects in modulating blood pressure and lowering blood sugar in people who have used it for some time, but it seems that observing the double effect of activities on these indicators requires long training programs, which future studies show. It will clarify more. Manuscript profile
List of Articles Insulin Resistance
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