Effect of MIIT training on visfatin and insulin resistance index in obese girls
Subject Areas : Sport Physiology
Anahita Nafisi
1
(Ph.D. Student in Exercise Physiology, Department of Sport Sciences, Kish International Campus, University of Tehran, Kish, Iran)
Bentolhoda Nasrabadi
2
(MSc, department of exercise physiology, east Tehran branch, Islamic Azad University, Tehran, Iran. ORCID: 0000-0001-7049-4702)
Mohammadreza Mohseni
3
(PhD of exercise Physiology, member of the performance improvement committee, Paralympic Committee, Tehran, Iran)
Keywords: Obesity, Insulin Resistance, Visfatin, MIIT,
Abstract :
Background: Visfatin is a new adipocyte which is highly expressed in visceral adipose tissue and has similar effects with insulin in the body. The purpose of this study was to investigate the effect of moderate intensity interval training on visfatin and insulin resistance index in obese girls. Material and Methods: In this semi-experimental study, 18 obese girls aged 12 -14 years were selected voluntarily and divided into two groups: training and control randomly. The training program included 8 weeks, 3 sessions a week, each week for 30 minutes running at 70% of the target heart rate in the first week to the fourth week and 75% in the fifth to the eight weeks. Blood samples were taken 24 hours before and 48 hours after the training program and the research variables were measured using specific methods. Analysis of covariance ANCOVA was used. The significance level was considered as p <0.05. Results:.The results of the current paper showed that the visfatin , Insulin resistance index, insulin and maximal oxygen consumption (vo2max) were increased in experimental group, which was significant only for the values of vo2max (P = 0.001). Body weight, body fat percentage, body mass index or BMI and glucose variables decreased in the experimental group. Conclusion: Today obesity is become a worldwide health issue and in this research paper we could show that longer training sessions with adequate intensity and volume have beneficial effects and they are suggested to make optimal changes in visfatin levels and reduce insulin resistance in obese girl.
1. Rezaian N, khosravi N, Sori R. Changes of visfatin concentration, insulin resistance index and lipids profile following 10 weeks of swimming endurance training in obese women, Journal of Sport Physiology and Physical Activity, 2011; 3(2), 429. https://joeppa.sbu.ac.ir/article_98578.html
2. Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature. 2006 Dec 14;444(7121):875-80. doi: 10.1038/nature05487. PMID: 17167476.
3. Fukuhara A, Matsuda M, Nishizawa M, Segawa K, Tanaka M, Kishimoto K, Matsuki Y, Murakami M, Ichisaka T, Murakami H, Watanabe E, Takagi T, Akiyoshi M, Ohtsubo T, Kihara S, Yamashita S, Makishima M, Funahashi T, Yamanaka S, Hiramatsu R, Matsuzawa Y, Shimomura I. Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science. 2005 Jan 21;307(5708):426-30. doi: 10.1126/science.1097243.
4. López-Bermejo A, Chico-Julià B, Fernàndez-Balsells M, Recasens M, Esteve E, Casamitjana R, Ricart W, Fernández-Real JM. Serum visfatin increases with progressive beta-cell deterioration. Diabetes. 2006 Oct;55(10):2871-5. doi: 10.2337/db06-0259. PMID: 17003355.
5. Chang YH, Chang DM, Lin KC, Shin SJ, Lee YJ. Visfatin in overweight/obesity, type 2 diabetes mellitus, insulin resistance, metabolic syndrome and cardiovascular diseases: a meta-analysis and systemic review. Diabetes Metab Res Rev. 2011 Sep;27(6):515-27. doi: 10.1002/dmrr.1201. PMID: 21484978.
6. Fedewa MV, Gist NH, Evans EM, Dishman RK. Exercise and insulin resistance in youth: a meta-analysis. Pediatrics. 2014 Jan;133(1):e163-74. doi: 10.1542/peds.2013-2718. Epub 2013 Dec 2. PMID: 24298011.
7. Fenkci S, Sarsan A, Rota S, Ardic F. Effects of resistance or aerobic exercises on metabolic parameters in obese women who are not on a diet. Adv Ther. 2006 May-Jun;23(3):404-13. doi: 10.1007/BF02850161. PMID: 16912022.
8. Seo DI, So WY, Ha S, Yoo EJ, Kim D, Singh H, Fahs CA, Rossow L, Bemben DA, Bemben MG, Kim E. Effects of 12 weeks of combined exercise training on visfatin and metabolic syndrome factors in obese middle-aged women. J Sports Sci Med. 2011 Mar 1;10(1):222-6. PMID: 24149317; PMCID: PMC3737906.
9. Taghian F, Zolfaghary M, Hedayati M. Effect of 12 weeks aerobic exercise on visfatin level and insulin resistance in obese women. RJMS. 2014; 20 (116) :35-44. URL: http://rjms.iums.ac.ir/article-1-2943-en.html
10. Pagano, M. and K. Gauvreau, Principles of biostatistics. 2018: Chapman and Hall/CRC.
11.Plowman, S.A. and D.L. Smith, Exercise physiology for health fitness and performance. 2013: Lippincott Williams & Wilkins
12. Angurani H, H.M., Halabchi F ,Mazaheri R Exercise and disease.Sports Medicine Research Center. Tehran University of Medical Sciences, 2008. First Ed: 4-6.
13.Cureton TK Jr. Interpretation of the oxygen intake test. What is it? Am Correct Ther J. 1973 Jan-Feb;27(1):17-23. PMID: 4571740.
14. Racil G, Ben Ounis O, Hammouda O, Kallel A, Zouhal H, Chamari K, Amri M. Effects of high vs. moderate exercise intensity during interval training on lipids and adiponectin levels in obese young females. Eur J Appl Physiol. 2013 Oct;113(10):2531-40. doi: 10.1007/s00421-013-2689-5. Epub 2013 Jul 4. PMID: 23824463.
15. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985 Jul;28(7):412-9. doi: 10.1007/BF00280883. PMID: 3899825.
16. Sheikholeslami Vatani, D. and S. Moradi, Visfatin, insulin and insulin resistance response to two methods of exercise order in overweight men. Sport Physiology, 2014. 6(22): p. 69-80. https://spj.ssrc.ac.ir/article_263.html?lang=en
17. Haider DG, Schaller G, Kapiotis S, Maier C, Luger A, Wolzt M. The release of the adipocytokine visfatin is regulated by glucose and insulin. Diabetologia. 2006 Aug;49(8):1909-14. doi: 10.1007/s00125-006-0303-7. Epub 2006 May 31. PMID: 16736128.
18. Moghadasi, M., & Mohammadi Domieh, A., & Khajehlandi, A., & Rostami, A. (2012). Comparing the Effects of 8 weeks of Resistance and endurance training on plasma visfatin in middle-aged men. Sport Physiology (Research On Sport Science), 4(15), 39-49. https://www.sid.ir/en/journal/ViewPaper.aspx?id=292102
19. Saghebjoo M, D.S., Afzalpour ME , Hedayati M, Effects of aerobic and resistance training on plasma visfatin levels in overweight women. Koomesh 2012. 13 (2): 225-232. URL: http://koomeshjournal.semums.ac.ir/article-1-1166-en.html
20. ERDEM, G., et al., Therapeutic lifestyle change intervention in metabolic syndrome decreases plasma visfatin levels. AJCI, 2008. 2(2): p. 58-62. https://www.researchgate.net/publication/26598776_Therapeutic_lifestyle_change_intervention_in_metabolic_syndrome_decreases_plasma_visfatin_levels
21. Mellick PF, Feger BJ, Oberlin DJ, Davis PG, Wideman L. High-Intensity Exercise and Carbohydrate Supplementation do not Alter Plasma Visfatin. J Sports Sci Med. 2017 Mar 1;16(1):69-76. PMID: 28344453; PMCID: PMC5358034.
22. Soori R, Khosravi N, Yazdandoust Baygi H, Khademi H. The Effect of Continual and Alternative Aerobic Training intensity on Visfatin and RBP4 Serum Levels in Obese Women with Type II Diabetes. jms. 2016; 3 (4) :1-9. URL: http://jms.thums.ac.ir/article-1-292-en.html
23. Tahmasebi V, G.M., Arefirad T, Hoovanloo F, Response of inflammatory markers and insulin resistance to a circadian resistance exercise session in healthy men. Journal of Diabetes and Metabolism of Iran, 2012. 11 (5):455-63. URL: http://ijdld.tums.ac.ir/article-1-30-fa.html
24. Rostami A , H.A., Norouzikamareh MH, Comparison of the Effects of 8-Week Aerobic and concurrent trainings on Visfatin Levels and Insulin Resistance in Women. Quarterly Journal of Sport Sciences, 2014. 14(4):21-36.
25. Tashakorizadeh M, M.M., The effect of 10 weeks resistance training on HSP70 and insulin resistance in diabetic women Type2. Sports Sciences 2016. 8(3): 341-351.doi: 10.22059/JSB.2016.59509
26. Khajehlandi A, Abed Natanzi H, Nikbakht H. The Effect of Swimming and Aloe Vera Extract on Serum of Visfatin Levels, and the Ratio of Triglycerides to High-Density Lipoproteins and Glucose in Streptozotocin-Induced Diabetic Male Rats. J Arak Uni Med Sci. 2017; 20 (3) :39-47. http://jams.arakmu.ac.ir/article-1-4892-en.html
27. B, A., The effect of resistance training on some factors of physical fitness and inflammatory markers in overweight men. Sports Sciences, 2013. (4): 49 – 64.
28. Fayazi, B., et al., The Effect Aerobic Training on Functional Capacity and Percent Body Fat in Women with Moderate Multiple Sclerosis (MS). Journal of Arak University of medical sciences, 2013. 16(70): p. 97-87. http://jams.arakmu.ac.ir/browse.php?a_id=1768&sid=1&slc_lang=en