Influence of Β-Hydroxy-Β-Methyl Butyrate Supplementation on Strength, Muscle and Liver-Damage Indices Induced by Dual Pyramid Resistance Training in Beginner Bodybuilders
Subject Areas : Sport Nutrition
Soleyman Ansari
1
,
Shahram Gholamrezaei
2
*
,
Fahimeh AdibSaber
3
,
Mohammad Moradnia
4
1 - PhD -Exercise Physiology, Department of Physical Education, Rasht Branch, Islamic Azad University, Rasht, Iran
2 - Assistant Professor, Department of Physical Education, Rasht Branch, Islamic Azad University, Rasht, Iran
3 - Assistant Professor, Department of Physical Education, Rasht Branch, Islamic Azad University, Rasht, Iran
4 - MA in Exercise Physiology, Department of Physical Education, Faculty of Humanities, Islamic Azad University, Rasht Branch, Rasht, Iran
Keywords: β-Hydroxy-β-Methyl butyrate, muscle strength, liver-damage markers, muscle-damage indices, dual pyramid resistance training,
Abstract :
Background: It has been suggested that ingesting supplements decrease muscle soreness, increase muscle strength, hypertrophy, and health-related indices. This study investigated the influence of 8-week β-Hydroxy-β-Methyl butyrate (HMB) supplementation combined with a dual pyramid resistance exercise program on strength, muscle, and liver-damage indices (ALT, AST, CK, and LDH) and body mass index (BMI) in beginner bodybuilders. Materials and Methods: A total of 40 beginner bodybuilders was randomized to an intervention group (resistance training + HMB supplementation) and a control group (resistance training + placebo) for 8 weeks. Blood samples and body measurements were taken at baseline and after the end of the intervention. The subjects were evaluated for BMI, 1 repetition maximum (1RM) bench press and leg press prior to and after the training intervention. In addition, blood samples were obtained before and after 8-week resistance training to evaluate creatine kinase (CK), lactate dehydrogenase (LD), aspartate aminotransferase (AST), and alanine aminotransferase (Johnson et al.) responses. Results: After 8 weeks of HMB ingestion, serum levels of CK (p<0.001), LDH (p<0.014), and ALT (p<0.009) of participants in the experimental group significantly decreased compared to the placebo group. Furthermore, The HMB group showed greater gains compared with the placebo group in 1RM leg and bench press (p<0.001). Regarding BMI and AST serum levels, there were no significant differences between groups. Conclusion: The results of the present study showed that HMB supplementation may attenuate the resistance exercise-induced muscle and liver damage indices and have beneficial effects on muscle strength.
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