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      • Open Access Article

        1 - The Effects of Coenzyme Q10 Supplementation with Two Consecutive Soccer Games on Stress Oxidative and Muscle Injury Markers in Male Collegiate Soccer Players
        Ehsan Arabzadeh
        Background: This study aimed to investigate the effect of coenzyme Q10 consumption for fourteen days on the response of some indicators of oxidative stress and muscle damage following two consecutive football matches in college players Materials and Methods: for this p More
        Background: This study aimed to investigate the effect of coenzyme Q10 consumption for fourteen days on the response of some indicators of oxidative stress and muscle damage following two consecutive football matches in college players Materials and Methods: for this purpose, 24 football players (with an average age of 20.08±12.1 years, a weight of 63.28±65.1 kg and a maximum oxygen consumption of 53.12± 0.98 ml /per /kg of body weight) The three groups were studied over a fourteen-day period. The control group did not receive these supplements and exercise activities, but the experimental groups included the placebo group (300 mg aspartame) and the coenzyme Q10 group (300 mg ubiquinone supplement) during the course in addition to receiving a placebo or supplement the two 90-minute football matches were less than 48 hours apart. Then, according to the research plan, blood samples were collected from the subjects in two stages 24 hours before and after the period and MDA, LDH, CK and AST indices were measured. Dependent t-test, one-way analysis of variance and Tukey's post hoc test were also used. Results: The results showed a significant difference between serum coenzyme Q 10 supplementation with serum MDA (P = 0.000) and AST (P = 0.006) concentrations from two consecutive football matches, while LDH levels (P = 0.970) and serum CK (P = 0.911) did not change significantly. Conclusion: Overall, the results show that supplementing coenzyme Q10 before and during a two-week match can have anti-oxidant benefits, so it can be recommended to college soccer players. Manuscript profile
      • Open Access Article

        2 - Chronic L-Carnitine Supplementation on Exercise Performance, Blood Lactate, and Exercise-Induced Oxidative Stress in Resistance-Trained Males
        Ebrahim Fallah
        Background: The purpose of the present study is to investigate the effect of Chronic L-Carnitine Supplementation on Exercise Performance, Blood Lactate, and Exercise-Induced Oxidative Stress in Resistance-Trained Males Materials and Methods: We examined 35 resistance-t More
        Background: The purpose of the present study is to investigate the effect of Chronic L-Carnitine Supplementation on Exercise Performance, Blood Lactate, and Exercise-Induced Oxidative Stress in Resistance-Trained Males Materials and Methods: We examined 35 resistance-trained (1y) male participants (25±2y, 79.8±8.9 kg, 16.1±5.53% body fat) for 9-wk of L-carnitine supplementation in conjunction with resistance training on exercise performance, blood lactate, and exercise-induced oxidative stress. Randomized, placebo-controlled, double-blind treatment of a (1) no intervention, no supplement Control (CON, n=12), (2) maltodextrose Placebo (PLA, 2 g/d, n=11) or (3) L-carnitine (LCR, 2 g/d, n=12). Exercise performance, post-exercise blood lactate (BL) and oxidative stress markers were analyzed at weeks 3, 6, and 9. The PLA and LCR groups followed a specific resistance training program (4 d/w, upper body/lower body split) for a 9-wk. Data were analyzed by GLM and presented as mean (SD) or change (95% CI). Primary outcomes were total lifting volume for the bench (BP) and leg press (LP). Results: The results a significant increase in BP lifting volume at wk-6 (139 kg, 95% CI 49.1, 230) and wk-9 (238 kg, 95% CI 132, 343) for LCR. Similar results were observed for LP. We also observed a significant increase in Wingate mean power (63.4 W, 95% CI 30.5, 96.3) and peak power (239 W/kg, 95% CI 104, 374) at wk-9 for LCR as well as a significant reduction in post-exercise BL levels and oxidative stress responses. No differences were observed in body composition. Conclusion: These findings indicate that LCR supplementation improves exercise performance and attenuates the blood lactate and oxidative stress response to resistance training. Manuscript profile
      • Open Access Article

        3 - Effect of Aerobic Training along with Garlic on Oxidative Stress Index in Obese Women with High Blood Pressure
        Ghasem  Torabi Palat Kaleh Mostafa  Kazemi Ahmad Abdi Asieh   Abbassi Daloii Masoomeh Alsadat Mirshafaei
        Background: A large amount of evidence shows that oxidative stress plays a central role in hypertension pathophysiology. The aim of this study was to examine effect of aerobic training along with Garlic on oxidative stress index in obese women with high blood pressure. More
        Background: A large amount of evidence shows that oxidative stress plays a central role in hypertension pathophysiology. The aim of this study was to examine effect of aerobic training along with Garlic on oxidative stress index in obese women with high blood pressure. Materials and Methods: In this clinical trial study, 36 postmenopausal obese women with hypertension were purposefully and accessibly selected from Sari and were simple randomly divided into four groups Control (C), Aerobic Training (AT), Garlic (G) and Aerobic Training +Garlic (ATG). The training groups participated in a progressive aerobic training for eight weeks, three sessions a week (55% to 65% of the reserved heart rate and for 30 to 55 min). The groups of G and ATG were provided 1000 mg of garlic supplement for eight weeks (After breakfast and dinner). Two days before and after the protocol, blood samples were taken in fasting state. SPSS 16.0 software was used for statistical analysis. Data were analyzed using ANCOVA at p<0.05. Results: The results showed that the levels of malondialdehyde (MDA) (P=0.0001) decrease significantly in the experimental groups. Also, superoxide dismutase (SOD) (P=0.001), glutathione peroxidase (GPX) (P=0.000) and catalase (CAT) (P=0.001) in the experimental groups increased significantly compared to the C group. The amount of SOD, GPx and CAT in the ATG group was significantly higher than the AT and G group (p≤0/05). Conclusion: It seems that AT and G has interactive effects on reducing Oxidative Stress in obese women with high blood pressure. Manuscript profile
      • Open Access Article

        4 - Investigating the Relationship between Depression and Physical Activity Index Following Short-Term Stress Induction: An Animal Study
        Maedeh  Poureskandar Saleh Rahmati Zahra Entezari Marzieh  Balali
        Background: Examining the impact of short-term stress on depressive-like behavior and motor activity in rats is a crucial aspect of behavioral and neuroscience research. Short-term stress can influence rats' depressive-like behavior and decrease their motor activity. Th More
        Background: Examining the impact of short-term stress on depressive-like behavior and motor activity in rats is a crucial aspect of behavioral and neuroscience research. Short-term stress can influence rats' depressive-like behavior and decrease their motor activity. The purpose of this study was to investigate the effect of short-term stress on depressive-like behavior and the running index of male Wistar rats, as well as the relationship between the two variables. Materials and Methods: Examining the impact of short-term stress on depressive-like behavior and motor activity in rats is a crucial aspect of behavioral and neuroscience research. Short-term stress can influence rats' depressive-like behavior and decrease their motor activity. The purpose of this study was to investigate the effect of short-term stress on depressive-like behavior and the running index of male Wistar rats, as well as the relationship between the two variables. Results: Short-term stress significantly increased the 24-hour running index (P=0.01). The depression-like behavior of rats after stress induction did not show any significant difference. There was no significant relationship between the amount of running and depressive-like behavior (P=0.13). Conclusion: Based on the present findings, short-term stress caused an increase in the activity of male Wistar rats, which was not related to depressive-like behavior. Manuscript profile