Acute Co-Ingestion of Caffeine and Sodium Bicarbonate on Performance the and biochemical indices of fatigue in male cross-fitters
Subject Areas : Sport Nutrition
mahdi reza gholizadeh
1
*
,
Reza Behdari
2
*
1 - گروه تربیت بدنی و علوم ورزشی دانشگاه آزاد اسلامی واحد زنجان
2 - Department of Physical Education and Sport Sciences, W T.C., Islamic Azad University, Tehran, Iran.
Keywords: sodium bicarbonate, caffeine, CrossFit, fatigue, anaerobic power,
Abstract :
Introduction: This study is designed to investigate the effects of acute sodium bicarbonate and caffeine administration on anaerobic power levels and biochemical markers of fatigue present in elite male CrossFit athletes' blood before a training session.
Methodology: The research included 20 male athletes skilled in CrossFit who volunteered to participate. They were randomly categorized into four groups: the sodium bicarbonate group (5 participants), the caffeine group (5 participants), the sodium bicarbonate and caffeine combination group (5 participants), and the placebo group (5 participants). The first group ingested 3mg of sodium bicarbonate per kg/BW, whereas the second group ingested 6mg of caffeine per kg/BW. The third group followed the same protocol, ingesting sodium bicarbonate and caffeine, which were provided in gelatin capsules one hour before their rigorous CrossFit workout. The placebo group consumed pills containing cellulose. The Burpee and Thruster movements were among the most arduous workouts. Following the conclusion of these exercise sessions, all participants undertook the RAST assessment. Blood samples were collected from fasting patients before and after these events to document and assess glucose, ammonia, and lactic acid variations. The hypotheses of this study were evaluated using the MANCOVA test with a significance threshold of P≥0.05.
Results: The group that received caffeine and sodium bicarbonate demonstrated significantly higher maximal and average anaerobic power than the placebo group. Nonetheless, the observed difference was minimal when evaluated against the outcomes of the caffeine or sodium bicarbonate groups administered individually. Conversely, the tiredness index variable in the same combination group was significantly lower than that of the caffeine or sodium bicarbonate groups. Nevertheless, this disparity was negligible in comparison to the placebo group. Compared to the placebo group, the simultaneous consumption of caffeine and sodium bicarbonate resulted in a significant decrease in lactic acid and ammonia levels in blood samples collected post-training. No statistically significant changes in glucose levels were seen across the groups (P<0.05).
Conclusion: The findings indicate that the combined ergogenic effects of caffeine and sodium bicarbonate can enhance anaerobic performance while mitigating fatigue and its associated biochemical markers through simultaneous consumption.
Keywords: caffeine, sodium bicarbonate, anaerobic power , fatigue, CrossFit
1. Ranjbar, R., Kordi, M. R., Gaeini, A. A. The Effect of Caffeine Ingestion on Anaerobic Power; Fatigue Index and Blood lactateLlevels in Boys Athlete Students. Journal of Sport Biosciences, 2009; 1(1): 123-136.
2. Gustav Claudino J, Gabbett T.J, Bourgeois F, de Sá Souza H, Chagas Miranda R, Mezêncio B, Soncin R, Alberto Cardoso Filho C, Bottaro M, Jose Hernandez A, Carlos Amadio A & Cerca Serrão J. (2018). CrossFit Overview: Systematic Review and Meta-analysis. Sports Medicine 4, 11.
3. Rahimi, M. R., Jafari, A., Golpasandi, H. The effect of caffeine ingestion on anaerobic performance and fatigue index in the morning and the evening times.. Journal of Applied Health Studies in Sport Physiology, 2017; 4(1): 60-67. doi: 10.22049/jassp.2019.26549.1220
4. behdari,Reza, Ghasemi,Soudabeh ,Mousavi Sadati,Seyed Kazem. The Effect of One Session of the Exhaustive Exercise & Caffeine Consumption on Muscle Fatigue Levels & Anaerobic Power of the Professional Female Karatekas. Journal of Sports Physiology and Athletic Conditioning, 2021;2(16-30).
5. Rezaei S, Akbari K, Gahreman DE, Sarshin A, Tabben M, Kaviani M, Sadeghinikoo A, Koozehchian MS, Naderi A. Caffeine and sodium bicarbonate supplementation alone or together improve karate performance. J Int Soc Sports Nutr. 2019 Oct 17;16(1):44. doi: 10.1186/s12970-019-0313-8. PMID: 31623659; PMCID: PMC6798418.
6. Marriott M, Krustrup P, Mohr M. Ergogenic effects of caffeine and sodium bicarbonate supplementation on intermittent exercise performance preceded by intense arm cranking exercise. J Int Soc Sports Nutr. 2015 Feb 27;12:13. doi: 10.1186/s12970-015-0075-x. PMID: 25750597; PMCID: PMC4351945
7. Bahrambeygi, B., Abbaspoor, M., Moflehi, D., Rouholamini, F. The effect of combined beta-alanine and caffeine supplementation on performance, fatigue index, and blood lactate of teenage male karatekas. Research in Exercise Nutrition, 2023; 2(2): 72-61. doi: 10.22034/ren.2024.140494.1053
8. Christensen PM, Shirai Y, Ritz C, Nordsborg NB. Caffeine and Bicarbonate for Speed. A Meta-Analysis of Legal Supplements Potential for Improving Intense Endurance Exercise Performance. Front Physiol. 2017 May 9;8:240. doi: 10.3389/fphys.2017.00240. PMID: 28536531; PMCID: PMC5422435.
9. Babaei, M., Soltani, M., Hadi, S., Rezagholizadeh, M. Effect of Acute Supplementation with Caffeine and Arginine Alpha-Actoglutarate on Strength Performance in Young Elite Weightlifters. Research in Exercise Nutrition, 2023; 1(4): 1-10. doi: 10.22034/ren.2023.140137.1029
10. Sassone J, Muster M, Barrack MT. Prevalence and Predictors of Higher-Risk Supplement Use Among Collegiate Athletes. J Strength Cond Res. 2019 Feb;33(2):443-450. doi: 10.1519/JSC.0000000000002979. PMID: 30531412.
11. Khodadadi D, Azimi F, Eghbal Moghanlou A, Gursoy R, Demirli A, Jalali P, Behdari R, Seyedheydari M. Habitual Caffeine Consumption and Training Status Affect the Ergogenicity of Acute Caffeine Intake on Exercise Performance. Sports Health. 2025 Feb 4:19417381251315093. doi: 10.1177/19417381251315093. Epub ahead of print. PMID: 39905628; PMCID: PMC11795567.
12. Grgic J, Mikulic P. Caffeine ingestion acutely enhances muscular strength and power but not muscular endurance in resistance-trained men. Eur J Sport Sci. 2017 Sep;17(8):1029-1036. doi: 10.1080/17461391.2017.1330362. Epub 2017 May 24. PMID: 28537195.
13. Kaçoğlu, C.; Kirkaya, İ.; Ceylan, H.İ.; de Assis, G.G.; Almeida-Neto, P.; Bayrakdaroğlu, S.; Chaves Oliveira, C.; Özkan, A.; Nikolaidis, P.T. Pre-Exercise Caffeine and Sodium Bicarbonate: Their Effects on Isometric Mid-Thigh Pull Performance in a Crossover, Double-Blind, Placebo-Controlled Study. Sports 2024, 12, 206. https://doi.org/10.3390/sports12080206
14. Ziyaiyan, A., Shabkhiz, F., & Hofmeister, M. (2023). Supplementation of caffeine and sodium bicarbonate together could not improve performance and performance-related factors in CrossFit participants: a randomized, double-blind, placebo-controlled study. Journal of the International Society of Sports Nutrition, 20(1). https://doi.org/10.1080/15502783.2023.2206390
15. Wilmore, J. H &, Costill, D. L. (2008). Fisiología del esfuerzo y del deporte: Editorial Paidotribo.
16. Siegler JC, Hirscher K. Sodium bicarbonate ingestion and boxing performance. J Strength Cond Res. 2010 Jan;24(1):103-8. doi: 10.1519/JSC.0b013e3181a392b2. PMID: 19625976.
17. Cameron SL, McLay-Cooke RT, Brown RC, Gray AR, Fairbairn KA. Increased blood pH but not performance with sodium bicarbonate supplementation in elite rugby union players. Int J Sport Nutr Exerc Metab. 2010 Aug;20(4):307-21. doi: 10.1123/ijsnem.20.4.307. PMID: 20739719.
18. Rodak K, Kokot I, Kratz EM. Caffeine as a Factor Influencing the Functioning of the Human Body-Friend or Foe? Nutrients. 2021 Sep 2;13(9):3088. doi: 10.3390/nu13093088. PMID: 34578966; PMCID: PMC8467199.
19. Green JM, Wickwire PJ, McLester JR, Gendle S, Hudson G, Pritchett RC, Laurent CM. Effects of caffeine on repetitions to failure and ratings of perceived exertion during resistance training. Int J Sports Physiol Perform. 2007 Sep;2(3):250-9. doi: 10.1123/ijspp.2.3.250. PMID: 19168925.
20. Schneiker KT, Bishop D, Dawson B, Hackett LP. Effects of caffeine on prolonged intermittent-sprint ability in team-sport athletes. Med Sci Sports Exerc. 2006 Mar;38(3):578-85. doi: 10.1249/01.mss.0000188449.18968.62. PMID: 16540848.
21. Grgic J. Effects of Combining Caffeine and Sodium Bicarbonate on Exercise Performance: A Review with Suggestions for Future Research. J Diet Suppl. 2021;18(4):444-460. doi: 10.1080/19390211.2020.1783422. Epub 2020 Jun 25. PMID: 32583697.
22. Hamidi, Robabeh. (1397).The effect of Beta-alanine and consumption on blood Bicarbonat, lactate, cortisol, blood HP, and young men working Karate for 4 weeks. Master Thesis. Azad University of East Tehran.
23. Sharifi, Gholamreza. Tagiyan, Farzaneh. Babaei mazraeh no, Alireza. Muhammadi, Fardin.(1392). Determine the effect of Sodium Bicarbonat consumption on anaerobic performance of non-athleric men. Volume 5. Number 4.
24. Grgic J, Grgic I, Del Coso J, Schoenfeld BJ, Pedisic Z. Effects of sodium bicarbonate supplementation on exercise performance: an umbrella review. J Int Soc Sports Nutr. 2021 Nov 18;18(1):71. doi: 10.1186/s12970-021-00469-7. PMID: 34794476; PMCID: PMC8600864.
25. Danković, Goran, Nemanja Stanković, Nikola Milošević, Vladimir Živković, Luca Russo, Gian Mario Migliaccio, Alin Larion, Nebojša Trajković, and Johnny Padulo. 2022. "Effects of Sodium Bicarbonate Ingestion on Recovery in High-Level Judokas" International Journal of Environmental Research and Public Health 19, no. 20: 13389. https://doi.org/10.3390/ijerph192013389
26. Crowe MJ, Weatherson JN, Bowden BF. Effects of dietary leucine supplementation on exercise performance. Eur J Appl Physiol. 2006 Aug;97(6):664-72. doi: 10.1007/s00421-005-0036-1. Epub 2005 Oct 29. PMID: 16265600.
27. Mohr M, Rasmussen P, Drust B, Nielsen B, Nybo L. Environmental heat stress, hyperammonemia and nucleotide metabolism during intermittent exercise. Eur J Appl Physiol. 2006 May;97(1):89-95. doi: 10.1007/s00421-006-0152-6. Epub 2006 Feb 17. PMID: 16485104.