The Effect of Resistance Training on The Changes in Serum Angiogenesis Stimulating Factors and The Progression of Retinopathy in Diabetic Patients
Subject Areas : Sport Physiology
Alireza Babaei Mazreno
1
*
,
Ismail Babaei
2
1 - Department of Sport Sciences, Islamic Azad University of Isfahan, Khorasgan Branch, Isfahan, Iran.
2 - Retina specialist, Faculty of Sadoughi University of Medical Sciences, Yazd, Iran.
Keywords: VEGF and NO, Endurance training, Retinopathy, Type 2 diabetes,
Abstract :
Background: Diabetic retinopathy is one of the most serious complications of Retina microvascular disorder, so the aim of this study was to investigate the effect of resistance training on changes in serum regressive stimulating factors and retinopathy progression in diabetic patients.
Materials and Methods: 24 men with type 2 diabetes without retinopathy symptoms were selected purposefully and randomly divided into two groups of 12 experimental controls. The experimental group performed 6 months of resistance training, three sessions per week with 65% intensity and 5% overload after all 6 sessions. Before and after 6 months, growth factor concentrations of vascular endothelium, nitric oxide and fasting blood sugar were measured and recorded, and finally the data were analyzed using correlated t-test, independent t and chi square. The meaning level was less than 0.05.
Results: Comparison of pre-test and post-test changes between the control and experimental groups showed that no (P=.001) and VEGF (P=.001) of the subjects after 6 months of resistance training had a significant difference with the control group, but there was no significant difference between the control and experimental groups.
Conclusion: A period of resistance training can increase growth factor derived from endothelium and plasma nitric oxide in diabetic patients and it may be hypothesized that exercise, in addition to controlling diabetes through increasing these factors, may also be effective in preventing retinopathy.
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